Iterative Usage of Fixed and Random Effect Models for Powerful and Efficient Genome-Wide Association Studies
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چکیده
منابع مشابه
Iterative Usage of Fixed and Random Effect Models for Powerful and Efficient Genome-Wide Association Studies.
False positives in a Genome-Wide Association Study (GWAS) can be effectively controlled by a fixed effect and random effect Mixed Linear Model (MLM) that incorporates population structure and kinship among individuals to adjust association tests on markers; however, the adjustment also compromises true positives. The modified MLM method, Multiple Loci Linear Mixed Model (MLMM), incorporates mul...
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Efficient Design and Analysis of Genome-wide Association Studies
OF THE DISSERTATION Efficient Design and Analysis of Genome-wide Association Studies
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Genome Wide Association Studies, Next Generation Sequencing and Their Application in Animal Breeding and Genetics: A Review
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ژورنال
عنوان ژورنال: PLOS Genetics
سال: 2016
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.1005767